Platelet Function With Various Storage Techniques

Northwell Health

Status and phase: Withdrawn; Phase 2

Conditions: Platelet Dysfunction Due to Drugs

Treatments: Biological: Placebo; Biological: Infusion of Platelets

Study type: Interventional

Funder types: Other

Identifiers

NCT03338660

16-XXXX-SIUHN

Details and patient eligibility

About

Platelet function will be tested in individuals on antiplatelet medications to determine the optimal storage methodology.

Full description

Subjects will undergo administration of antiplatelet drugs and then will receive platelets stored in a variety of methods. Platelet function will be measured serially.

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal subjects

Exclusion criteria

• Pre existing antiplatelet drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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0 participants in 3 patient groups, including a placebo group

Control (Placebo)

Placebo Comparator group

Description:

Subjects will receive infusion of placebo (saline).

Treatment:

Biological: Placebo

Platelet storage routine

Active Comparator group

Description:

Subjects will receive infusion of platelets stored by routine method.

Treatment:

Biological: Infusion of Platelets

Biological: Infusion of Platelets

Platelet storage experimental

Experimental group

Description:

Subjects will receive infusion of platelets stored by a novel methodology.

Treatment:

Biological: Infusion of Platelets

Biological: Infusion of Platelets