Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery (BIANCA)

Medical University of Graz

Status: Completed

Conditions: Postoperative Bleeding

Study type: Observational

Funder types: Other

Identifiers

NCT01606865

BIANCA

Details and patient eligibility

About

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.

Enrollment: 207 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days
• spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery)

Exclusion criteria

• concomitant medication with warfarin
• renal insufficiency needing dialysis
• concomitant therapy with GPIIB/IIIA Antagonists
• expected duration of operation >30min

Trial design

207 participants in 1 patient group

elective and acute non-cardiac surgery