Platelet Reactivity and MES During CEA

UMC Utrecht

Status: Unknown

Conditions: Aspirin Resistance; Ischemic Stroke; Carotid Artery Stenosis; Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT01547039

NL33061.051.10

Details and patient eligibility

About

The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Al patients undergoing elective carotid endarterectomy

Exclusion criteria

• Patients requiring a blood transfusion prior to surgery
• Patients with an inappropriate temporal bone window for transcranial Doppler (TCD)
• Patients on vitamin K antagonists or antiplatelet treatment other then aspirin
• Patients with an artificial cardiac valve

Trial design

200 participants in 1 patient group

Carotid endarterectomy (CEA)

Description:

Patients undergoing carotid endarterectomy