Platelet-Rich Fibrin Dressing in the Management of Free Gingival Graft

Damascus University

Status: Completed

Conditions: Gingival Recession

Treatments: Device: A Platelet-Rich Fibrin dressing; Procedure: A free gingival graft; Device: A non-eugenol-based dressing

Study type: Interventional

Funder types: Other

Identifiers

NCT03589235

UDDS-Perio-02-2018

Details and patient eligibility

About

Evaluation of two dressing materials; a Platelet-Rich Fibrin (PRF) dressing and a non-eugenol-based (Coe-Pak™) dressing in the management of free gingival graft and donor site palatal wound.

Full description

Evaluation of the usage of platelet-rich fibrin dressing in the management of free gingival graft and donor site palatal wound by evaluation of pain score, healing tissue in both donor and receiving sites, coverage of gingival recession, and the gain of attached gingiva.

A total of 20 subjects will be invited to participate in this study from the patients seeking treatment at the Department of Periodontology, Faculty of Dentistry, Damascus University.

The study has been approved by the investigator's local Review Board. Subjects will be recruited according to specific inclusion criteria. After completion of medical and dental history questionnaires, patients will sign a consent form after being advised about the nature of the study.

Patients will be allocated into two groups (10 patients each). A Platelet-Rich Fibrin (PRF) dressing will be used in both donor and receiving sites in the test group, while a non-eugenol-based (Coe-Pak™) dressing will be used in both donor and receiving sites in the control group .

Donor site working time, bleeding (BLE), colour match (CM), pain and re-epithelization (EP) will be evaluated.

Enrollment: 20 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of Syrian descent.
• Systemically healthy.
• Attached gingival width ≤ 2 mm.
• Presence of type II (Miller Classification) of gingival recession.

Exclusion criteria

• Smoking.
• Pregnancy or lactating.
• Presence of any systematic diseases can affect the periodontal surgery.
• Subjects with significant moderate to severe periodontal disease.
• Patients under orthodontic treatment
• Presence of restorative materials (e.g. crown)
• Subjects have failed to maintain good plaque control.
• Subjects having previous surgical treatment for covering the recession in the chosen area.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

A Platelet-Rich Fibrin dressing

Experimental group

Description:

A Platelet-Rich Fibrin dressing (PRF) will be used in both donor and receiving sites after a free gingival graft.

Treatment:

Procedure: A free gingival graft

Device: A Platelet-Rich Fibrin dressing

A non-eugenol-based dressing

Experimental group

Description:

A non-eugenol-based dressing (Coe-Pak™) will be used in both donor and receiving sites after a free gingival graft.

Treatment:

Device: A non-eugenol-based dressing

Procedure: A free gingival graft