Platelet Rich Fibrin in Soft Tissue Healing After Implant Uncovering

G. d'Annunzio University

Status

Completed

Conditions

Healing Surgical Wounds

Treatments

Procedure: Application of L-PRF on the donor area

Procedure: Secondary intention healing of the donor area

Study type

Interventional

Funder types

Other

Identifiers

NCT05375357

19102021

Details and patient eligibility

About

This study represents a prospective, controlled and randomized clinical trial assessing the effects of L-PRF on the healing time of the donor area and on the patient's postoperative morbidity in the 4 weeks following the Apically Positioned Flap (APF) procedure in the uncovering phase of two-stage implants.

A total of 40 patients were recruited and divided into two groups. The implant uncovering procedure in the test group was performed with APF and application of L-PRF on the donor area. Patients in the control group, on the other hand, were treated with APF alone, leaving the donor area to heal by secondary intention.

Enrollment

40 patients

Sex

All

Ages

19 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

to have at least one implant in the maxilla with a quantity of vestibular keratinized gingiva < 2 mm
to be in good systemic health
to have a good oral hygiene (FMPS and FMBS < 20%)

Exclusion criteria

systemic diseases: coagulation disorders; medications affecting periodontal status in the previous 6 months; pregnancy or lactation;
smoking habits;
peri-implant surgery on the experimental sites.