Platelet-Rich Plasma and Hip Osteoarthritis

Sisli Hamidiye Etfal Training and Research Hospital

Status: Completed

Conditions: Hip Osteoarthritis

Treatments: Other: intra-articular PRP injection

Study type: Interventional

Funder types: Other

Identifiers

NCT04820231

191

Details and patient eligibility

About

To evaluate the effect of platelet-rich plasma (PRP) injection on pain, function and quality of life in patients with hip osteoarthritis.

Full description

After being informed about the study and potential risk, all patients giving written informed consent will undergo study entry.

Each patient received three times intra-articuler injections of PRP under ultrasound guidance, and they were administered once a week.

Baseline: Visual Analog Scale (VAS) including movement, rest and night, the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and SF-36 assessment

1st month: VAS, WOMAC and SF-36 assessment

3rd month: VAS, WOMAC and SF-36 assessment

6th month: VAS, WOMAC and SF-36 assessment

Enrollment: 35 patients

Sex: All

Ages: 50 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hip pain VAS > 4
• Grade 1 and 2 osteoarthritis according to the Kellgren-Lawrence classification
• No pathologies in the laboratory and coagulation parameters

Exclusion criteria

• Rheumatological disease with hip involvement
• Systemic active infection
• Severe cardiovascular disease
• Malignancy
• NSAID usage in the last week
• History of hip joint surgery
• History of traumatic hip injury
• Hgb values < 11 gr/dl
• Platelets values < 150.000 / µl
• History of bleeding disorder

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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35 participants in 1 patient group

PRP injection group

Other group

Description:

Intra-articular PRP injection with ultrasound guidance Three times PRP injections with an interval of one week

Treatment:

Other: intra-articular PRP injection