Platelet Rich Plasma (PRP) as a Treatment for ACHILLES Tendon Tears

Clalit Health Services

Status and phase: Completed; Phase 3; Phase 2

Conditions: Achilles Tendon Tear

Treatments: Biological: placebo; Biological: PRGF

Study type: Interventional

Funder types: Other

Identifiers

NCT00731068

MeirMc07om0090CTIL

2000

Details and patient eligibility

About

To review the influence of patient derived PRGF on the healing process of Achilles tendon after a surgical correction of a complete tear.

Full description

Autologous platelet-rich matrices may aid in post surgical patients by promoting and accelerating tissue healing because of the release of growth factors including transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF) from platelet alpha-granules.

Enrollment: 50 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A complete tear of Achilles tendon
• Age 18-50 years old

Exclusion criteria

• under 18 year of age
• pregnancy
• physical or mental disabilities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

PRGF

Treatment:

Biological: PRGF

2

Placebo Comparator group

Treatment:

Biological: placebo