Platelet Rich Plasma (PRP) Injections For Knee Osteoarthritis

Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Procedure: PRP injections

Study type: Observational

Funder types: Other

Identifiers

NCT04852380

PRP-Knee Osteoarthritis

Details and patient eligibility

About

It was conducted a prospective study with a series of 153 patients treated with PRP injections in patient affected by knee osteoarthritis. One independent observer performed clinical and functional evaluations at T0 (recruitment), T1 (one month after the injection), T2 (three months after the last injection) and T3 (six months after the last injection).

The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Knee Score Society (KSS) score and the Visual Analogue Scale (VAS) were evaluated and recorded for each patient at each follow up.

Enrollment: 153 patients

Sex: All

Ages: 40 to 81 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 40 and 81;
• Body mass index (BMI) between 21.5 and 29.3;
• Chronic history (for at least 4 months) of knee joint pain;
• Radiographically documented knee osteoarthritis of grades 1 to 3 (Kellgren-Lawrence (K-L) radiographic classification scale)

Exclusion criteria

• Radiographically severe documented knee osteoarthritis of grade 4 (K-L radiographic classification scale);
• Previous femur and tibia fractures;
• Knee previous surgical treatment (e.g., arthroscopy);
• Hyaluronic acid infiltration within the previous six months;
• Hemoglobin levels <10 g/dL;
• History of oncohematological disease, infections, or immunodepression

Trial design

153 participants in 1 patient group

Patients treated by PRP injection

Treatment:

Procedure: PRP injections