Platelets for Acute Wound Healing
Status
Conditions
Treatments
Details and patient eligibility
About
This study will examine whether platelet gel positively affects wound healing. Platelet gel will be used to treat punch biopsy wounds and the results will be compared to results from wounds treated with a control treatment.
Full description
Platelets contribute to the healing process in soft tissue by providing the initial hemostasis that occurs following injury, a framework for fibrin matrix formation and contribution of growth factors.
According to the US National Institutes of Health, surgical procedures are considered a form of controlled injury, so many of the complications faced by surgery patients are very similar to those faced by trauma patients. Scientists are currently investigating ways to treat wounds caused by trauma, burns or surgical inventions with biological agents (i.e. growth factors) or new drugs. Growth factor priming of acute wound sites pre-activates the cellular and molecular components of tissue repair, prior to tissue injury.
Objectives are aimed at gathering information to establish evidence that autologous platelet gel positively effects the healing of acute wounds.
Sex
Ages
Volunteers
Inclusion criteria
- Normal volunteers
- 18 years old or older
Exclusion criteria
- Pregnant or lactating
- Diabetic, keloid former, collagen vascular disease
- Smoker
- Body mass index >30kg/m2
- Known history of HIV/AIDS; Hepatitis A, B, or C
- Bleeding disorder
- Aspirin, non-steroidal anti-inflammatory drug (NSAID) or anticoagulant user
- Cancer, or treatment for cancer, in past 5 years
Trial design
Primary purpose
Allocation
Interventional model
Masking
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal