Plethysmography Curve Variability Depending on the Breath Cycle

Czech Technical University in Prague

Status: Completed

Conditions: Respiration; Circulatory; Change; Apnea

Treatments: Other: Respiratory rate; Other: Tidal volume; Other: Apnea

Study type: Interventional

Funder types: Other

Identifiers

NCT05302219

Plethysmography2022

Details and patient eligibility

About

The aim of the study is to analyze the variability of plethysmography curve depending on the breath cycle (respiratory rate and tidal volume).

Full description

The plethysmography curve measured by finger sensors using pulse oximetry shows the changes in blood volume at the measured site. The presence of respiratory information within the pulse oximeter signal is a well-documented phenomenon. However, previous studies have mainly focused on extracting the respiratory rate from the plethysmography curve. The aim of this study is to analyze the variability of plethysmography curve as a function of both respiratory rate and tidal volume. Furthermore, the aim is to analyze the possibilities of apneic pause detection from the plethysmography curve.

Enrollment: 10 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers/students from the Czech Technical University in Prague

Exclusion criteria

• any acute illness
• pregnancy
• severe cardiovascular conditions
• severe asthma or other severe respiratory conditions
• diabetes
• hypotension or hypertension

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Measurement of plethysmography curve

Experimental group

Description:

Calm measurement of plethysmography curve using pulse oximetry with simultaneous monitoring of the breath cycle. In this experimental arm, participants will vary their breath cycle (different respiratory rates and different tidal volumes).

Treatment:

Other: Apnea

Other: Tidal volume

Other: Respiratory rate