Pneumological Acute Coronary Syndrom (ACS) Phenotyping Aachen (PAPA)

RWTH Aachen University

Status: Completed

Conditions: Acute Coronary Syndrom; Chronic Obstructive Pulmonary Syndrom

Study type: Observational

Funder types: Other

Identifiers

NCT02587481

15-057

Details and patient eligibility

About

In this open, monocentric, observational study acute coronary syndrom (ACS) patients will be characterized by pneumological examination concerning a concomitant chronic obstructive pulmonary disease (COPD). Often COPD coexists with ACS; therefore ACS patients benefit either from prevention or potential therapy of chronic hypoxia.

Full description

In this study patients with either non ST-segment-elevation myocardial infarction (NSTEMI) or ST-segment-elevation myocardial infarction (STEMI) will be included. After amnesis patients will undergo blood withdrawal, blood-gas analysis and examinations concerning pulmonary function (Bodyplethysmography). In addition to routine blood withdrawal for differential blood count, 9 ml blood sample is takenfor molecular analysis of relevant prognostic chronic obstructive pulmonary disease (COPD)-blood based biomarkers, an for establishing a library of biomaterial in form of a biobank.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written declaration of consent
• Patients with acute myocardial infarct which can be either non ST-segment-elevation myocardial infarct (NSTEMI) or ST-segment-elevation myocardial infarct (STEMI), in both cases exaggeration of cardiac ischaemic markers

Exclusion criteria

• Patients not fulfilling the incluson criterias or:
• Pregnant or breastfeeding women
• Participation in other studies
• Persons in depency from the sponsor or working with the sponsor
• Persons without mental ability or capacity to understand and follow the instructions of the investigator