Pneumoproteins Expression in the Organ Donor

University Hospital of Mont-Godinne

Status: Completed

Conditions: Primary Graft Dysfunction

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02032069

B406201112693

Details and patient eligibility

About

Primary graft dysfunction, a form of reperfusion pulmonary edema that occurs early after lung transplantation, shares key clinical and pathological features with acute lung injury and its more severe form, the acute respiratory distress syndrome. However, in contrast to acute lung injury/acute respiratory distress syndrome, in which biomarkers in plasma, urine and lung edema fluid have prognostic and pathogenetic value, the role of biomarkers in primary graft dysfunction has been less thoroughly explored. We will try in this study de determine the rule of pneumoproteins in the donor organ on the pulmonary edema in the recipient.

Enrollment: 20 patients

Sex: All

Ages: 5 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All the organ donors for lung grafts.

Exclusion criteria

none

Trial design

20 participants in 2 patient groups

NHBD

Description:

Non Heart Beating Donors

Treatment:

Other: no intervention

BDD

Description:

Brain death donors

Treatment:

Other: no intervention