Podocyturia as Predictive Factor for Pre-eclampsia (PEPOD1)

Civil Hospices of Lyon

Status: Completed

Conditions: Pre-Eclampsia

Treatments: Other: Podocyturia quantification

Study type: Observational

Funder types: Other

Identifiers

NCT03316430

69HCL17_0516

Details and patient eligibility

About

Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Podocyn could be identified in the urine, before proteinuria, a key element in the diagnostic of pre-eclampsia. Preventive treatment using aspirin could be administrated in early pregnancy. We hypothesized that podocyturia could be an early indicator of preeclampsia. This is a prospective, non-interventional, monocentric study.

Enrollment: 1,000 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women aged 18 years or more
• single pregnancy
• first planned prenatal visit before 16 weeks of gestation
• planned delivery at Hôpital Femme Mère Enfant in Lyon, France
• patient receiving information and non opposition to participate

Exclusion criteria

• multiple pregnancy
• pregnancy stopped
• antecedent of nephropathy
• inability to understand information provided
• prisoner or under administrative supervision
• fetal malformation, chromosomal anomalies
• preterm delivery for other reason that any hypertensive disorder of pregnancy or Intrauterine growth restriction

Trial design

1,000 participants in 1 patient group

Patients

Description:

Patients coming before 16 weeks of gestation at their first planned prenatal visit at the Hôpital Femme Mère Enfant, who planned to deliver at the Hôpital Femme Mère Enfant

Treatment:

Other: Podocyturia quantification