Point-of-Care Multiplex for Adult Patients With Severe Community-acquired Pneumonia

National Taiwan University

Status: Unknown

Conditions: Community-acquired Pneumonia; Critical Illness

Treatments: Diagnostic Test: Provide the panel report to the primary care physician

Study type: Interventional

Funder types: Other

Identifiers

NCT04835818

201901147RIND

Details and patient eligibility

About

Clinical Impact on Point-of-Care Multiplex PCR Testing for Critically Ill Adult Patients With Community-acquired Pneumonia - A cluster randomization study in ICU units within one medical center.

Full description

Point-of-Care Multiplex PCR Testing could narrow down the pathogens causing severe community-acquired pneumonia(CAP). Our hypothesis is that the result of Point-of-Care Multiplex PCR Testing could help primary physician to reduce antibiotics use.

Enrollment: 60 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (age >20 y/o)
• ICU admission for acute respiratory failure due to community-acquired pneumonia by clinical diagnosis
• Treatment with endotracheal Intubation

Exclusion criteria

• Aspiration pneumonia (including witnessed aspiration and chronic bedridden status)
• Nosocomial infection

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Reporting

Experimental group

Description:

check point-of-care Multiplex PCR for pneumonia pathogens and report results to primary care physician

Treatment:

Diagnostic Test: Provide the panel report to the primary care physician

Usual Care

No Intervention group

Description:

check point-of-care Multiplex PCR for pneumonia pathogens but do NOT report results to primary care physician. Let primary care physician provide usual standard care