Polydextrose for Patients With Chronic Kidney Disease

Universidade Federal Fluminense

Status: Completed

Conditions: Chronic Kidney Diseases; Constipation

Treatments: Dietary Supplement: Polydextrose

Study type: Interventional

Funder types: Other

Identifiers

NCT05336305

DeniseMafra15

Details and patient eligibility

About

Constipation is a common complication in patients with chronic kidney disease (CKD), especially in hemodialysis (HD) patients. Reduced intake of fibre-rich food is among the most important causes of constipation. The study aims to investigate the possible influence of polydextrose (PDX) supplementation on constipation in patients with CKD on HD.

Enrollment: 40 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Chronic Kidney Disease
• Hemodialysis patients for more than 6 months
• Aged 18 years or older

Exclusion criteria

• Patients pregnant
• Smokers
• Using antibiotics in the last 3 months
• Autoimmune diseases
• Clinical diagnosis of infectious diseases
• Clinical diagnosis of Cancer
• Clinical diagnosis of AIDS

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

Placebo Group

Placebo Comparator group

Description:

Administration of corn starch daily for 2 months

Treatment:

Dietary Supplement: Polydextrose

polydextrose

Experimental group

Description:

Administration of 12g polydextrose daily for 2 months

Treatment:

Dietary Supplement: Polydextrose