Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75 (POLYVIH)

Centre Hospitalier Universitaire de Nice

Status: Begins enrollment this month

Conditions: Virus-HIV

Treatments: Other: interview with advanced practice nurse

Study type: Interventional

Funder types: Other

Identifiers

NCT07388394

25-PP-19

Details and patient eligibility

About

Since the advent of antiretroviral treatments, the life expectancy of people living with HIV (PLHIV) has increased significantly. In France, more than 30% of PLHIV are now over 50 years old. This population is exposed to high multimorbidity, leading to frequent polypharmacy, defined as the regular use of at least five medications. Polypharmacy also has a qualitative dimension, including potentially inappropriate prescriptions. It increases the risk of adverse effects and drug interactions and impairs quality of life. A coordinated geriatric approach is therefore essential to optimize care. Healthy aging, promoted by the WHO, aims to improve the lives of older people. In this context, a study will be conducted at the Nice University Hospital among PLHIV aged 75 and over. It will collect quantitative data, the results of which will enable us to consider, if necessary, adapting the care pathways of these patients whose needs are complex.

Enrollment: 136 estimated patients

Sex: All

Ages: 75+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV-positive
• Aged 75 or over
• Affiliated with the social security system
• Having expressed no objection to participating in the study

Exclusion criteria

• Refusal to participate
• Known severe cognitive impairment preventing the interview from being conducted
• Patient under guardianship or conservatorship

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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136 participants in 1 patient group

people living with HIV over the age of 75

Other group

Treatment:

Other: interview with advanced practice nurse