Polyunsaturated Fatty Acids Supplementation and Blood Metabolome

Poznan University of Life Sciences

Status: Unknown

Conditions: Healthy

Treatments: Other: The high PUFA diet group

Study type: Interventional

Funder types: Other

Identifiers

NCT03892486

LKB 1249/19

Details and patient eligibility

About

Analysis of the effect of dietary intervention based on increased polyunsaturated fatty acid intake on health. Specifically changes in blood lipid profile, as well as proteomic and metabolomic profiles of healthy adults will be analyzed.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• good health,
• proper body weight
• not meeting the needs for polyunsaturated fatty acids

Exclusion criteria

• increased body weight,
• limited communication to an extent that makes it impossible to carry out a food interview,
• eating disorders (according to food history),
• metabolic diseases,
• pregnancy,
• lactation,
• taking drugs that influence the metabolism of lipids or carbohydrates

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

The high PUFA diet group

Experimental group

Description:

This will receive detailed nutritional recommendations and will consume at least 4 table spoons of olive oil or 30 grams of nuts daily for 12 weeks.

Treatment:

Other: The high PUFA diet group

Control group

No Intervention group

Description:

The Control group will receive general nutritional recommendations based on Human Nutrition Recommendations for Polish Population.