Pomegranate Juice and Metabolic Syndrome

Urmia University of Medical Sciences

Status: Completed

Conditions: Metabolic Syndrome

Treatments: Other: placebo; Other: pomegranate juice

Study type: Interventional

Funder types: Other

Identifiers

NCT02298621

1175

Details and patient eligibility

About

The effect of pomegranate juice (PJ) intake on cardiovascular risks in subject with metabolic syndrome.

Full description

The effect of pomegranate juice (PJ) intake on cardiovascular risks in subject with metabolic syndrome in shabestar.

Enrollment: 30 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• presence of ≥3 of the following diagnostic of MetS:

  • serum TGs of at least 150 mg/dL,
  • waist circumference of more than 102 cm (40 in) in men and more than 88 cm (35 in) in women,
  • high-density lipoprotein (HDL) level less than 40 mg/dL in men and less than 50 mg/dL in women,
  • blood pressure 135/85 mm Hg or higher, or
  • fasting glucose 100 mg/dL or Higher

Exclusion criteria

• liver cirrhosis,
• chronic pancreatitis,
• gastrointestinal or connective diseases,
• kidney stones, or
• renal failure,
• alcohol Consumption,
• having an allergy to pomegranate juice,
• a change in diet,
• the large increase in LDL so that required drug treatment.
• use of statins of fibrates, corticosteroids, nitrates, acetyl-salicylic acid or other anti-platelet drugs, oral hypoglycemic drugs, nonsteroidal anti-inflammatory drugs, or drugs interfering with coagulation;
• pregnancy or lactation in the past 6 mo, supplementation with vitamins or antioxidants

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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30 participants in 2 patient groups, including a placebo group

pomegranate juice

Experimental group

Description:

pomegranate juice: 500 ml

Treatment:

Other: placebo

Other: pomegranate juice

placebo

Placebo Comparator group

Description:

sugar + aroma+ color: 500ml

Treatment:

Other: placebo

Other: pomegranate juice