Pomegranate Peel Extract for Primary Molar Pulpotomy

Tanta University

Status: Not yet enrolling

Conditions: Pulp Exposure, Dental; Pulpitis Reversible

Treatments: Procedure: Pulpotomy; Procedure: Radiation

Study type: Interventional

Funder types: Other

Identifiers

NCT07108738

#R-PED-7-25-3206

Details and patient eligibility

About

Pomegranate peel extract has demonstrated a range of potential uses in the biomedical industry in recent years because of its numerous benefits, which include anti-inflammatory, antibacterial, anti-apoptotic, antioxidant, and cell-regeneration-promoting qualities. Therefore, the purpose of this study will be to evaluate the clinical and radiographic efficacy of Pomegranate peel extract as a pulpotomy agent in primary teeth.

Full description

A total of sixty primary molars in thirty children aged between 4 and 8 years will be randomly divided into two groups: Group I, the Pomegranate peel extract group, and Group II, the MTA group. After pulpotomy treatment, all molars will be restored with stainless steel crowns. Follow-up will be done after 3, 6, and 9 months for clinical and radiographic assessment.

Enrollment: 30 estimated patients

Sex: All

Ages: 4 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Restorable primary molars with deep carious lesions.
• Absence of gingival swelling or sinus tract.
• Absence of spontaneous pain
• Absence of pain on percussion.
• Absence of discontinuity of lamina dura
• Absence of internal root resorption.
• Absence of external root resorption.
• Absence of inter-radicular or periapical bone destruction (radiolucency).

Exclusion criteria

• presence of spontaneous pain
• presence of gingival swelling or sinus tract
• presence of internal or external root resorption
• pain on percussion.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 2 patient groups

group 1: zinc oxide-pomegranate peel extract paste

Experimental group

Description:

30 primary molars will be treated with pomegranate peel extract freshly mixed with zinc oxide powder till it reaches a suitable consistency (1:1 ratio by volume) to cover pulp stumps

Treatment:

Procedure: Radiation

Procedure: Pulpotomy

group 2: MTA

Active Comparator group

Description:

30 primary molars will be treated with MTA to cover pulp stumps

Treatment:

Procedure: Radiation

Procedure: Pulpotomy