POPLITEAL SCIATIC NERVE BLOCK FOR DIABETIC FOOT SURGERIES

Alexandria University

Status: Unknown

Conditions: Diabetic Patient

Treatments: Drug: magnesium sulfate; Drug: bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04903743

0106292

Details and patient eligibility

About

Popliteal Sciatic nerve block is a regional technique that provides safe and reliable perioperative anesthesia and analgesia of lower leg and foot used in diabetic patients. Different additives have been used with local anaesthetics to achieve dense and prolonged block. Magnesium sulfate possesses analgesic properties owing to its effect on NMDA receptors.

Enrollment: 50 estimated patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• (ASA) II or III
• scheduled for diabetic foot surgeries.

Exclusion criteria

• Patients who refused the anaesthetic technique,
• whose BMI ≥ 35 kg/ m2,
• unable to properly describe postoperative pain to investigator (dementia, delirium, psychiatric and neurological disorders),
• patients with coagulopathy, skin infection at the site of injection,
• preoperative use of opioid or non-steroidal anti-inflammatory drugs,
• allergy or contraindication to studied medication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

group B

Placebo Comparator group

Description:

28ml of 0.25% bupivacaine and 2ml normal saline

Treatment:

Drug: bupivacaine

group BM

Active Comparator group

Description:

received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.

Treatment:

Drug: bupivacaine

Drug: magnesium sulfate