Population-based Study in Screening for Liver Fibrosis (LiverScreen)

Judit Pich Martínez

Status: Completed

Conditions: Liver Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT03789825

LiverScreen

Details and patient eligibility

About

Study to assess the prevalence of significant liver fibrosis in general population using Transient Elastography

Full description

This is a population-based study. Subjects will attend a primary care center where a physical examination, general blood test and transient elastography will be carried out. Only the group of patients with high-risk for liver fibrosis will be evaluated in a second visit at the University Hospital.

Enrollment: 30,000 patients

Sex: All

Ages: 40+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 40 years
• Able to give informed consent

Exclusion criteria

• Previously known chronic liver disease (including cholestasis). Patients with already known liver steatosis but no diagnosis of liver fibrosis or cirrhosis can be included
• Subjects with mental incapacity, language barrier, insufficient social support or any other reason considered by the investigator precluding adequate understanding or cooperation in the study
• Subjects with a history of current malignancy including solid tumors and hematologic disorders
• Subjects with significant extrahepatic disease that may impair short-term prognosis (including congestive heart failure New York Heart Association Grade IV, COPD GOLD >3)
• Subjects with kidney disease (serum creatinine >3mg/dL or under renal replacement therapy)