Porous and Non-porous Bone Grafts in Intra-bony Periodontal Defects

D

Dr. D. Y. Patil Dental College & Hospital

Status and phase

Completed
Phase 3
Phase 2

Conditions

Periodontal Disease

Treatments

Drug: Porous variant of Bioactive Glass.
Drug: Non porous variant of Bioactive Glass.

Study type

Interventional

Funder types

Other

Identifiers

NCT02463006
DYPDCH/12/PG16

Details and patient eligibility

About

Till date, no study has been reported in the literature where porous bioactive glass was used for the management of periodontal osseous defects. In this context, the present study is designed to assess the efficacy of the porous variant of bioactive glass and compare with that of nonporous variant using cone beam computed tomography.

Full description

OBJECTIVES: To evaluate clinically the periodontal healing with Porous variant of Bioactive Glass placed in the intra bony defects at an interval of 6 months. To evaluate clinically the periodontal healing with Non Porous variant of Bioactive Glass placed in the intra bony defects at an interval of 6 months. To evaluate the radiographic changes in the intra bony defect grafted with Porous variant of Bioactive Glass at baseline and an interval of 6 months. To evaluate the radiographic changes in the intra bony defect grafted with Non Porous variant of Bioactive Glass at baseline and an interval of 6 months. To compare clinically soft tissue healing for sites grafted with Porous variant of Bioactive Glass and sites grafted with Non Porous variant of Bioactive Glass in the treatment of periodontal intra bony defects at an interval of 6 months. To compare the radiographic changes for sites grafted with Porous variant and sites grafted with Non Porous of Bioactive Glass in the treatment of periodontal intra bony defects at an interval of 6 months.

Enrollment

10 patients

Sex

All

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

INCLUSION CRITERIA

  • Age: 18-55 years.
  • Probing Depth >5mm.

Exclusion criteria

EXCLUSION CRITERIA

  • History of periodontal treatment last six months.
  • Bleeding disorders.
  • Gross oral pathology.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

10 participants in 2 patient groups

porous bone graft group
Experimental group
Description:
Intervention: Flap surgery procedure with porous bone grafting (Periooglass)
Treatment:
Drug: Porous variant of Bioactive Glass.
Non-porous bone gaft group
Active Comparator group
Description:
Intervention: Flap surgery procedure with non-porous bone grafting (Novabone morsels)
Treatment:
Drug: Non porous variant of Bioactive Glass.

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems