Porphyromonas Gingivalis and Alzheimer's Disease (PGNEURO)

University Hospital Muenster

Status: Completed

Conditions: Periodontitis; Alzheimer's Disease; Dementia

Study type: Observational

Funder types: Other

Identifiers

NCT02109705

PG001

Details and patient eligibility

About

With this study the investigators would like to analyze the the role of periodontal disease and especially the role of Porphyromonas gingivalis in initiation and progression of Alzheimer's Disease.

Enrollment: 90 estimated patients

Sex: All

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 40-70
• caucasian origin
• dementia (Alzheimer's or other dementia)
• cognitive healthy (need for spinal anesthesia)

Exclusion criteria

• use of antibiotics within las 6 months
• pregnancy
• another illness explaining the symptoms in a better way
• smoking (>10 cigarettes)
• patients who have a legal custodian

Trial design

90 participants in 3 patient groups

Alzheimer's Disease

other Dementia

cognitive healthy