Portal Hypertension Using Magnetic Resonance Elastography

Yonsei University

Status: Completed

Conditions: Portal Hypertension; Magnetic Resonance Imaging

Treatments: Diagnostic Test: MRE

Study type: Observational

Funder types: Other

Identifiers

NCT05749198

CR317132

Details and patient eligibility

About

This prospective study was conducted in a tertiary university hospital. The investigators researched the correlation between MRE-assessed stiffness of the liver and spleen and the Hepatic venous pressure gradient (HVPG) values. Furthermore, the investigator evaluated whether MRE-assessed stiffness reflected changes in portal hypertension (PH) after administering non-selective beta-blockers (NSBBs).

Enrollment: 47 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosed liver cirrhosis
• requiring prophylactic treatment of esophageal varices

Exclusion criteria

• the coexistence of hepatocellular carcinoma
• refractory ascites who regularly underwent large-volume paracentesis
• the use of selective beta-blocker or carvedilol therapy for at least 4 weeks
• undergoing liver transplantation
• contraindication with magnetic resonance imaging