Position and Esophageal Pressure (pEsition)

Civil Hospices of Lyon

Status

Completed

Conditions

Acute Respiratory Distress Syndrome

Treatments

Other: head-bed position

Study type

Interventional

Funder types

Other

Identifiers

NCT02816359

69HCL16_0152

Details and patient eligibility

About

Esophageal pressure measurements are used in moderate/severe Accurate Respiratory Distress SyndromeARDS patients in order to set ventilator settings. There might be variations of the measured value according to the patient position (0° vs 30°) at the time of measurements.

Enrollment

11 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years
Acute respiratory failure defined by PaO2/FIO2< 300 mmHg or pH<7,35 and pCO2>45mmHg or Moderate or severe Accurate Respiratory Distress Syndrome ARDS defined by:
- New or worsening respiratory symptoms in the previous week.
- Bilateral opacities-not fully explained by effusions, lobar/lung collapse, or Nodules
- Respiratory failure not fully explained by cardiac failure or fluid overload
- PaO2/FIO2< 200 mmHg and PEEP ≥ 5 cm H2O and VT ≤6 ml/kg of Ideal Body Weight
Patient intubated or tracheotomized and receiving mechanical ventilation
Indication of esophageal measurement decided by the clinician

Exclusion criteria

Contraindication to naso-gastric tube insertion :
- Recent gastro-duodenal ulcer
- Stage III esophageal varices
Refractory intracranial hypertension
Unstabilized spine fracture
Surgical contraindication
Burns on more than 20 % of the body surface
Underlying disease with a life expectancy of less than one year
End-of-life decision before inclusion
Pregnant or breast-feeding patients
Subject deprived of freedom, minor, subject under a legal protective measure
Research team unavailability
Lack of medical care plan