Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study

University of Genova

Status: Not yet enrolling

Conditions: Respiratory Failure; Recruitment

Treatments: Procedure: Continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy

Study type: Observational

Funder types: Other

Identifiers

NCT06689020

PEP-RECRUIT

Details and patient eligibility

About

This single-center observational study aims to assess the effects of continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy on lung recruitment using electrical impedance tomography (EIT) in spontaneously breathing patients admitted to the intensive care unit.

Enrollment: 26 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who require pulmonary expansion and airway clearing as per clinical indication
• Patients who provide valid informed consent according to local regulations
• PaO2/FiO2 < 200 mmHg at inclusion
• Patient on the Airway Care Score (ACS) < 7

Exclusion criteria

• Refuse to participate
• Age < 18 years
• Hemodynamic instability, defined as systolic arterial pressure < 90 mmHg or mean pressure < 60 mmHg
• Contraindication to using an EIT (i.e., pacemaker or defibrillator)
• Inability to properly position the EIT device for anatomical reasons