Positive Pressure and Gravity Affect Volumetric Capnography

Hospital Privado de Comunidad de Mar del Plata

Status: Completed

Conditions: Hypoventilation

Treatments: Other: body positions

Study type: Interventional

Funder types: Other

Identifiers

NCT03853057

04112014

Details and patient eligibility

About

Volumetric capnography is an interesting and non-invasive tool for monitoring ventilation in mechanically ventilated patients. The aim of this study was to test the effect of positive pressure ventilation and different body positions on volumetric capnograms.

Full description

In this interventional study awake and healthy volunteers will be submitted to spontaneous, pressure support and control pressure ventilation using a tight nasal mask. Volumetric capnography and electrical impedance tomography (EIT) will be continuously recorded during the protocol. Different body positions were randomly tested. Analysis of global and regional distribution of ventilation using EIT will be matched with changes observed in volumetric capnography-derived parameters.

Enrollment: 10 patients

Sex: Male

Ages: 28 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• American Society Anesthesia physical status I.
• Age between 25-39 years old,
• Body mass index between 23-28 kg/m2,
• Non-smokers.

Exclusion criteria

• Presence of pulmonary or cardiac diseases.
• Abnormal spirometry.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

non-invasive ventilation

Experimental group

Description:

Non-invasive positive pressure at different body positions: sitting - supine - prone - right lateral and left lateral.

Treatment:

Other: body positions