ClinicalTrials.Veeva

Menu

Possibilities of Interpreting the Night-to-Day Ratio Specified by 24-hour Blood Pressure Monitoring (ABPM)

S

St. Anne's University Hospital Brno, Czech Republic

Status

Completed

Conditions

Cardiovascular Diseases

Treatments

Other: The cardiovascular exercise
Other: Combined aerobic-resistance exercise
Other: Ambulatory blood pressure monitoring

Study type

Interventional

Funder types

Other

Identifiers

NCT05264090
24H7D_ABPM

Details and patient eligibility

About

Specify the risk rate of incorrect patient classification based on night-to-day ratio specification from singular 24-h ABPM in comparison to the results of 7-day ABPM monitoring

Full description

The subjects in the study are divided into 4 groups:

group 1 (40 healthy men and women without exercise); group 2 (40 healthy exercise-training men and women); group 3 (40 patients with ischemic coronary artery disease without exercise); and group 4 (51 patients with ischemic coronary artery disease following cardiovascular rehabilitation).

The subject of the evaluation is the percentage rate of incorrect subject classification (dipper, non-dipper, extreme dipper, and risers) based on the mean blood pressure values for 7 days and from seven independent 24-hour cycles (the mean value mode).

Enrollment

171 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy volunteers (without any disease, including the cardiovascular ones, and without any kind of treatment)
  • Patients with chronic ischemic coronary artery disease
  • Patients treated with ACE inhibitors, beta-blockers or statins.
  • To visit routinely in the health centres where the study is carried out

Exclusion criteria

  • Age under 18 years,
  • Pregnant, or breast-feeding,
  • Patients on dialysis or being followed by nephrology,
  • Severe physical or cognitive limitations,
  • Intolerance to the method of measurement

Trial design

Primary purpose

Diagnostic

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

171 participants in 4 patient groups, including a placebo group

Group 1
Placebo Comparator group
Description:
Healthy volunteers without exercise
Treatment:
Other: Ambulatory blood pressure monitoring
Group 2
Sham Comparator group
Description:
Healthy exercise-training volunteers
Treatment:
Other: Combined aerobic-resistance exercise
Other: Ambulatory blood pressure monitoring
Group 3
Active Comparator group
Description:
Patients with ischemic coronary artery disease without exercise
Treatment:
Other: Ambulatory blood pressure monitoring
Group 4
Experimental group
Description:
Patients with ischemic coronary artery disease following cardiovascular rehabilitation
Treatment:
Other: The cardiovascular exercise
Other: Ambulatory blood pressure monitoring

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems