Post-COVID-19 Pneumo-hematocele (PHC)

Hospital General Ajusco Medio

Status: Completed

Conditions: COVID-19 Respiratory Infection

Treatments: Procedure: Pulmonary resection

Study type: Observational

Funder types: Other

Identifiers

NCT05067881

HGAM02

Details and patient eligibility

About

Introduction. As the COVID-19 pandemic has continued, an increasing number of long-term complications are emerging. Recently, the appearance of characteristic pulmonary lesions has been noted, being described as post COVID-19 pneumatocele. The aim of this study is to describe the clinical, histopathologic and imaging features of post COVID-19 pneumo-hematoceles (PHC) and secondarily to suggest a treatment algorithm in these patients.

Methods. A retrospective study was performed in patients admitted with diagnosis of SARS-CoV2 infection from March 2020 to September 2021 who presented PHC on imaging studies. Clinical and demographic variables were recorded and CT scans were analyzed. A logistic regression analysis was performed to determine the risk for rupture according to PHC characteristics.

It appears that PHC occurs secondary to encapsulation of blood accumulation, the result of micro capillary bleeding, with partial reabsorption of blood and subsequent air filling. The recommendation is to operate on patients with PHC of 5cm and those with persistent lesions of 3cm.

Enrollment: 37 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults with a positive protein chain reaction for SARS-CoV2,
• PHC on imaging studies.

Exclusion criteria

• loss of follow up
• age out of range.

Trial design

37 participants in 1 patient group

Pneumohematocele

Description:

Patients with SARS CoV-2 diagnosis and PHC on imaging studies

Treatment:

Procedure: Pulmonary resection