Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention (PrepareD)

Kaiser Permanente

Status: Completed

Conditions: Obese; Overweight; Metabolic Disorders; Postpartum

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT06067126

5R01DK125348 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial [NCT02346162] has an influence in the postnatal period. PrepareD is a cohort study (no intervention) that will address new specific aims through one in-person visit with mothers and children, dietary recalls, actigraphy, and the use of medical record weights. The goal is to collect data when the child is 3 years old. However, due to the COVID-19 pandemic, the investigators expanded the data collection window in order to collect data up to when the child is 5 years old. The investigators hypothesize that intervening on women before pregnancy is the key to breaking the multigenerational cycle of obesity.

Enrollment: 154 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Mother must be a Prepare [NCT02346162] participant who has experienced a viable pregnancy during the Prepare trial
• Child must be the first viable offspring born to a Prepare participant after consent into the Prepare study

Exclusion Criteria: None