Post-discharge Nutrition and Resistance Training in Surgical Patients (MaSu)

University of Copenhagen

Status: Completed

Conditions: Malnutrition; Surgery

Treatments: Dietary Supplement: Nutrition

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03327935

H-17000004

Details and patient eligibility

About

Randomized intervention by nutritional supplements and training in postoperative patients after discharge

Full description

Surgery combined with malnutrition is associated with loss of muscle mass and leads to serious consequences for the surgical patient. A majority of surgical patients continue to lose weight after discharge. Nutritional risk screening has not been fully implemented at Landssjúkrahúsið - the National Hospital of the Faroe Islands and therefore the prevalence of patients at nutritional risk is unknown. The aim of this study is to examine whether an intervention with independent nutritional supplements or an intervention combining nutritional supplements and resistance training is more effective in preventing loss of muscle mass than standard care in surgical patients following discharge. Secondary outcomes are changes in body weight, quality of life, muscle strength and activities of daily living. Furthermore, we want to screen hospitalized surgical patients for nutritional risk in order to get an estimate of the prevalence of nutritional risk.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to the surgical departments at Landssjúkrahúsið - National Hospital of Faroe Islands
• Aged 18 years or above
• One or more of the following surgical procedures: knee alloplasty, hip alloplasty, collum femoris fracture, back fracture, abdominal surgery, mamma surgery and other comprehensive surgery
• At nutritional risk according to screening

Exclusion criteria

• Minimally invasive surgery/Laparoscopic surgery
• Severely reduced kidney function (p-creatinin>250 mikromol/l) or dialysis
• Terminal illness
• Inability to cooperate in tests or exercises due to cognitive function or dementia
• Admitted to intensive care unit
• Inability to speak or understand Faroese, Danish or English
• Consent according to national regulations not obtainable

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

Nutrition

Experimental group

Description:

Oral nutritional supplements and dietetic advice

Treatment:

Dietary Supplement: Nutrition

Nutrition and exercise

Experimental group

Description:

Oral nutritional supplements, dietetic advice and exercise training

Treatment:

Dietary Supplement: Nutrition

Control

No Intervention group

Description:

Standard Hospital Procedure