Post-exercise Hypotension After a Power Training Session in Older Adults With Hypertension

Hospital de Clinicas de Porto Alegre

Status: Completed

Conditions: Hypertension

Treatments: Behavioral: Power Training Session

Study type: Interventional

Funder types: Other

Identifiers

NCT03615625

85210618.1.0000.5327

Details and patient eligibility

About

The main purpose of the present study was to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension. As secondary outcomes, the investigators compared post-exercise hypotension, BP variability, and endothelial function between older men and women with hypertension.

The working hypothesis was that a single bout of power exercise would decrease both office and 24 h BP in comparison to a non-exercising control session and men and women would respond differently after a power training session.

Full description

Participants randomly performed two experimental sessions: power exercise training (PT) and non-exercising control at seated rest (Con). They maintained their current antihypertensive medications throughout the trial. Each session was composed of 20 min of rest in the supine position, 40 min of PT or Con protocols, and 60 min of rest in supine position after protocols. The PT was composed of 3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds. During the Con, the participants remained seated rest on the same exercise machines, but without any exercise. Standardized office BP was performed before and during the first hour (in intervals of 15 min) after exercise and control sessions. Together with the office BP evaluation in the pre and post sessions, the endothelium-dependent brachial vascular function was evaluated using Flow-mediated dilation. Afterwards, participants underwent 24h ambulatory BP monitoring..

Enrollment: 24 patients

Sex: All

Ages: 60 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Office blood pressure between 130-179 and 80-110 mmHg for systolic and diastolic blood pressure, respectively;
• Non-engaged in structured programs of exercise for the last 3 months since the beginning of this study;
• Able to perform the proposed exercises.

Exclusion criteria

• Underlying cardiovascular disease previously diagnosticated by a doctor, occurred in the last 24 months, such as: acute myocardial infarction, angina, stroke or heart failure;
• Diseases that reduce life expectancy;
• Smokers and ex-smokers for less than six months;
• BMI > 39.9 kg/m²
• diabetic proliferative retinopathy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

24 participants in 2 patient groups

Control session

No Intervention group

Description:

Control session without any exercise. The participants remained in seated rest throughout 40 min

Power Training Session

Experimental group

Description:

The power training session lasted 40 min, in which the participants performed a resistance exercise session using high velocity contractions during the exercises characterizing a power training session

Treatment:

Behavioral: Power Training Session