Post-operative Analgesia in Elective, Soft-tissue Hand Surgery

Alexander Payatakes, M.D.

Status and phase

Terminated

Phase 4

Conditions

De Quervain Disease

Ganglion Cyst

Trigger Finger

Carpal Tunnel

Treatments

Drug: Acetaminophen/Hydrocodone

Drug: Acetaminophen/Ibuprofen

Study type

Interventional

Funder types

Other

Identifiers

NCT02029235

IRB - 00076

Details and patient eligibility

About

The purpose of this research study is to find out which combination of pain medications following surgery work the best and result in the fewest side effects.

Full description

This is a prospective, randomized, double-blind study comparing the efficacy of acetaminophen/hydrocodone (AH) to acetaminophen/ibuprofen (AIBU) in providing adequate post-operative pain relief in elective, soft tissue hand surgery patients.

Enrollment

72 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age greater than or equal to 18
Male or Female (non-pregnant)
Elective, soft tissue hand surgery indicated based on diagnosis made by either clinical exam or diagnostic studies (ie nerve conduction study, EMG) or a combination of the two (carpal tunnel release, trigger finger release, first dorsal compartment release, ganglion cyst excision, second extensor compartment release)
Subjects are capable of giving informed consent

Exclusion criteria

Allergy to study medication
Any pre-existing pain condition requiring analgesia
Fibromyalgia
Recent upper gastrointestinal bleeding
Coagulopathy (primary or medication-related)
Renal impairment
Liver disease
Pregnancy
Patients who consent to the study but require unexpected admission, including those requiring admission resulting from operative complications, will be excluded before randomization