Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery (POCD)

HealthPartners Institute

Status: Completed

Conditions: Post Operative Cognitive Dysfunction

Treatments: Procedure: Elective Orthopedic Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT04267328

A19-224

Details and patient eligibility

About

Post-operative cognitive dysfunction (POCD) is a common concern for aging patients undergoing elective orthopedic surgery and significantly effects health outcomes. This study aims to evaluate the incidence of and risk factors associated with post-operative cognitive dysfunction in aging patients without prior history for mild cognitive impairment or dementia.

Enrollment: 47 patients

Sex: All

Ages: 50 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥50 and ≤90
• Any patient undergoing elective orthopedic surgery for hip, knee, or shoulder replacement (as defined by diagnostic codes: M16.0, M16.12, M16.11, M17.0, M17.12, M17.11, M19.011, M19.012)

Exclusion criteria

• History of cognitive impairment of dementia
• Montreal cognitive assessment (MoCA) <26
• History of Parkinson's disease, progressive supranuclear palsy, corticobasal degeneration, normal pressure hydrocephalus, Huntington's disease, stroke, seizure disorder, brain tumor, or brain surgery
• History of surgery requiring anesthesia within the past 3 months

Trial design

47 participants in 1 patient group

Patients having surgery

Description:

Older adults undergoing elective orthopedic surgery.

Treatment:

Procedure: Elective Orthopedic Surgery