Post Operative Pain Control for Distal Radius Surgery: Does Exparel Injected at the Surgery Site Improve Postoperative Pain Scores at 24 and 48 Hours ?

The University of Texas System (UT)

Status and phase: Withdrawn; Phase 4

Conditions: Post Operative Pain

Treatments: Drug: Group B (Bupivacaine HCL plus supraclavicular block); Drug: Group A (Exparel plus supraclavicular block); Drug: Group C(supraclavicular block only)

Study type: Interventional

Funder types: Other

Identifiers

NCT04540848

HSC-MS-20-0430

Details and patient eligibility

About

The purpose of this study is to see if Exparel, used intraoperatively by injecting at the surgical site, followed by a Supraclavicular nerve block with bupivacaine in the recovery room, will provide better pain scores for patients at 24 and 48 hours post operatively than, 1)Bupivacaine Hydrochloride (HCL) injection at the surgical site, with a supraclavicular block in Post-anesthesia care unit(PACU), or 2)a supraclavicular block in PACU without any kind of injection at the surgical site.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• distal radius fractures
• undergoing Open reduction internal fixation (ORIF) at Lyndon B Johnson Ambulatory Surgical Center (LBJ ASC)

Exclusion criteria

• pregnancy
• history of chronic pain conditions
• currently taking opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 3 patient groups

Exparel plus supraclavicular block

Experimental group

Treatment:

Drug: Group A (Exparel plus supraclavicular block)

Bupivacaine HCL plus supraclavicular block

Active Comparator group

Treatment:

Drug: Group B (Bupivacaine HCL plus supraclavicular block)

supraclavicular block only

Active Comparator group

Treatment:

Drug: Group C(supraclavicular block only)