Post-operative Pain Reduction

Minia University

Status: Unknown

Conditions: Effects of the Elements

Treatments: Drug: Conventional calcium hydroxide paste; Drug: Calcium hydroxide nanoparticle; Drug: Combined Calcium hydroxide with silver nanoparticle

Study type: Interventional

Funder types: Other

Identifiers

NCT04338633

314

Details and patient eligibility

About

Recruited patients with necrotic pulp after application of conventional calcium hydroxide paste are assigned to group, Calcium hydroxide nanoparticle group and Combined Calcium hydroxide with silver nanoparticle group and record postoperative pain afterwards.

Full description

The investigator will recruit patients who are found eligible to the criteria, conventional calcium hydroxide paste , Calcium hydroxide nanoparticle and Combined Calcium hydroxide with silver nanoparticle . After 48 hours, patients will be randomly assigned to removal of intracanal medication

After the visit, patients will be asked to record post operative pain by Numerical Rating Scale)in a given sheet

Enrollment: 30 estimated patients

Sex: All

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• • Medically free patients.

  • Patient's age between 25-50 years.
  • Sex includes both male and female.
  • Radiographic evidence of a periapical radiolucent lesion associated with tooth.
  • Necrotic pulp as indicated by thermal pulp testing.
  • No history of previous endodontic treatment of the tooth.

Exclusion criteria

• • Teeth with unfavorable conditions for rubber-dam application.

  • Teeth with acute periapical abscesses swelling.
  • Medically compromised patients.
  • Immature teeth with open apices.
  • Multi rooted teeth.
  • Pregnant women.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 3 patient groups

Conventional calcium hydroxide paste

Active Comparator group

Description:

Application of Conventional calcium hydroxide paste

Treatment:

Drug: Conventional calcium hydroxide paste

Calcium hydroxide nanoparticle

Experimental group

Description:

Application of Calcium hydroxide nanoparticle

Treatment:

Drug: Calcium hydroxide nanoparticle

Combined Calcium hydroxide with silver nanoparticle

Experimental group

Description:

Application of Combined Calcium hydroxide with silver nanoparticle

Treatment:

Drug: Combined Calcium hydroxide with silver nanoparticle