Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy

University of Oklahoma (OU)

Status and phase: Terminated; Phase 3; Phase 2

Conditions: Hernia, Inguinal; Analgesia; Pain

Treatments: Other: placebo; Drug: Gabapentin

Study type: Interventional

Funder types: Other

Identifiers

NCT00735124

14002

Details and patient eligibility

About

The study will investigate the effects of single dose pre-operative oral dose of gabapentin (1200) on post -operative pain scores and oral analgesic requirements.

Full description

The study will benefit patients in reducing post-operative pain scores as well as reduction in oral analgesic consumption. Gabapentin has been shown to reduce post operative pain pain scores in breast surgery, hysterectomy , spinal surgery, orthopedic and thyroid surgery

Enrollment: 5 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects having elective surgery with open unilateral Inguinal herniorraphy

Exclusion criteria

• Non elective surgery
• Patients currently on gabapentin therapy
• Patient hypersensitive to gabapentin surgery
• History of alcohol or drug abuse
• Patients who are pregnant or who are nursing

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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5 participants in 2 patient groups, including a placebo group

Single pre-op dose of Gabapentine

Active Comparator group

Description:

Active treatment with the study drug

Treatment:

Drug: Gabapentin

Placebo

Placebo Comparator group

Description:

Placebo arm for blinding the medication

Treatment:

Other: placebo