Post-Operative Therapy for Nausea or Vomiting

University of California (UC) Davis

Status and phase: Terminated; Phase 4

Conditions: Vomiting; Nausea

Treatments: Drug: Ondansetron; Procedure: Acupressure

Study type: Interventional

Funder types: Other

Identifiers

NCT03075163

932163

Details and patient eligibility

About

This is a single site, prospective, randomized controlled study designed to evaluate the impact of acupressure when used as an initial treatment before rescue medications in the treatment of post-operative nausea and/or vomiting at UCD.

Full description

Each individual will only participate in the post anesthetic care unit starting from when the patient's nurse or anesthesiology team deems that the patient needs treatment for PONV. It ends when the patient is discharged from anesthesiology care.

Patients will be asked to score nausea before randomized treatment of acupressure or medication, and to score nausea after treatment.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for elective surgery requiring general anesthesia

Exclusion criteria

• Age less than 18 years
• Adults unable to give primary consent
• Pregnancy
• Prisoners
• Unable to access pericardial 6 acupressure point bilaterally post procedure
• Allergy to Ondansetron

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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300 participants in 2 patient groups

Acupressure

Experimental group

Description:

Manual pressure will be applied on the wrists bilaterally.

Treatment:

Procedure: Acupressure

Ondansetron

Active Comparator group

Description:

Ondansetron (Zofran) is used for the treatment of nausea and vomiting.

Treatment:

Drug: Ondansetron