Post-Surgical Non-Small Cell Lung Cancer (NSCLC) Follow-up

Intergroupe Francophone de Cancerologie Thoracique

Status: Completed

Conditions: Non-Small-Cell Lung Carcinoma

Treatments: Procedure: Radiological Arm; Procedure: Scannographic arm

Study type: Interventional

Funder types: Other

Identifiers

NCT00198341

IFCT-0302

Details and patient eligibility

About

The follow-up of patients operated on for lung cancer is heterogeneous. An intensive follow-up including routine clinic visits, chest X-rays, chest computed tomography (CT) scans and fiberoptic bronchoscopies might detect more small, potentially curable, recurrences and second cancers. However, as it appears in the American Society of Clinical Oncology (ASCO) recommendations, a large randomized study is necessary to evaluate the survival impact of such a follow-up strategy. This is the main objective of this IFCT-0302 study, which is a large randomized controlled study conducted in France comparing this intensive follow-up to a follow-up with only routine clinic visits and chest X-rays.

Enrollment: 1,775 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• completely resected stage I, II, IIIa, and T4 due to satellite tumor nodule(s) N0-2 NSCLC

Exclusion criteria

• stage IIIb to IV NSCLC

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

1,775 participants in 2 patient groups

1

Experimental group

Description:

Radiological arm (Clinical Visit + X-Ray Chest)

Treatment:

Procedure: Radiological Arm

2

Experimental group

Description:

Scan ARM : Clinical Visit + X-Ray Chest + CT-Scan + Fibroscopy (for squamous type)

Treatment:

Procedure: Scannographic arm