Post-transplant Cancer Incidence and Survival in Patients With or Without Pre-transplant Cancer

Uppsala University

Status: Completed

Conditions: Kidney Failure; Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT02491580

PreTXCa

Details and patient eligibility

About

Patients with previous malignancies have increasingly been accepted for renal transplantation. However, post-transplant malignancy risk and survival rates of these patients are unknown. Our aim was to assess if previous malignancies pose an unnecessarily high risk of post-transplant malignant tumours and if the organs as a resource are too limited for investment in this patient group.

Enrollment: 2,370 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Kidney transplanted patients from January 1982 through December 2013 with or without a pre transplant cancer.

Exclusion criteria

• Simultaneous kidney+pancreas transplantation.
• Islet cell transplanted patients
• Undiagnosed malignancies at the time of transplantation
• Death within a week after transplantation
• First transplantation at another hospital

Trial design

2,370 participants in 2 patient groups

KTx Uppsala

Description:

Patients who have received a kidney transplant in Uppsala.

KTx Europe

Description:

Patients who have received a kidney transplant in Uppsala.