Post Traumatic Stress Among Relatives of Brain-dead, Withdrawal of Life Support, and Sudden Death Patients

Centre Hospitalier Universitaire de Nīmes

Status: Terminated

Conditions: Stress Disorders, Post-Traumatic

Treatments: Other: IES-R and HDAS scores

Study type: Observational

Funder types: Other

Identifiers

NCT01412502

2009-A00848-49 (Other Identifier)

PHRC-N/2009/CB-01

Details and patient eligibility

About

This study concerns the nearest relatives of patients who have passed away within 3 days of admission to an ICU due to: (1) brain death with multiple organ donation +/- tissues or (2) death via limitation and / or cessation of active treatment (LATA) without brain death or (3) sudden death of a previously healthy patient (no physical or mental limitations; MacCabe score = 0) within 3 days of admission to ICU without LATA nor brain death. Our primary objective is to determine the proportion of nearest relatives at risk for post traumatic stress disorder as defined by an Impact of Event Scale score greater than 37, and to compare this factor between the three above-mentioned groups.

Enrollment: 119 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants are the nearest relatives (or "person-of-trust") of a patient who has passed away in an intensive care unit (ICU). The cause of death must fall into 1 of the following three categories: (1) brain death with multiple organ donation +/- tissues; (2) death via limitation and / or cessation of active treatment (LATA) without brain death; (3) sudden death of a previously healthy patient (no physical or mental limitations; MacCabe score = 0) within 3 days of admission to ICU without LATA nor brain death
• The participant must be one of the following (roman numerals indicate prioritization in choice of participants, if needed): (i) designated "person-of-trust"; (ii) spouse/partner of the deceased; (iii) parent of the deceased; (iv) child of the deceased; (v) sibling of the deceased.

Exclusion criteria

• Patient deceased after 3 days of ICU care without LATA
• The deceased was under 18 years old
• The deceased was over 70 years old
• Refusal to participated
• Participant does not speak French
• The participant is under judicial protection, under tutorship or curatorship
• The participant is deaf or mute
• The deceased has no nearest relative

Trial design

119 participants in 3 patient groups

Brain death with organ donation

Description:

Participants in this group are the nearest relatives (or "person-of-trust") of a patient who has passed away within 3 days of admission to an intensive care unit. The cause of death includes brain death with multiple organ donation +/- tissues.

Treatment:

Other: IES-R and HDAS scores

Limitation/cessation of active treatment

Description:

Participants in this group are the nearest relatives (or "person-of-trust") of a patient who has passed away within 3 days of admission to an intensive care unit. The cause of death includes limitation/cessation of active treatment without brain death.

Treatment:

Other: IES-R and HDAS scores

Sudden death

Description:

Participants in this group are the nearest relatives (or "person-of-trust") of a patient who has passed away within 3 days of admission to an intensive care unit. The cause of death was sudden death of a previously healthy patient (no physical or mental limitations; MacCabe score = 0) within 3 days of admission to ICU without LATA nor brain death.

Treatment:

Other: IES-R and HDAS scores