Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft (MPM)

Cairo University (CU)

Status: Unknown

Conditions: Bone Resorption

Treatments: Other: autogenous bone; Other: Mineralized plasmatic matrix

Study type: Interventional

Funder types: Other

Identifiers

NCT03014388

CairoU MPM

Details and patient eligibility

About

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

Full description

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.

-PICO Population(P) : Patients with defective posterior maxillary alveolar ridge. Intervention (I) :Implant placement and ridge augmentation with MPM. Comparator (C) : Autogenous bone graft. Outcome (O) : Patient satisfaction - Implant stability.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients systemically free.
2. Patients with posterior maxillary defective ridges indicated for sinus lift procedure.
3. Cases with 5 mm bone height or less are included in the study.
4. Age between 18 and 50 years.
5. Both sexes.
6. Patients physically able to tolerate surgical and restorative procedures.
7. Good oral hygiene.
8. Highly motivated patients.

Exclusion criteria

1. Patients allergic to local anesthetic agent.
2. Medium and heavy smokers.
3. Pregnant females.
4. Presence of any pathosis in the pre-implant site.
5. Presence of any mucosal disease.
6. History of oral radiotherapy.
7. History of prolonged steroids use.
8. Psychological disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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20 participants in 2 patient groups

Autogenous bone graft (Gold Standard).

Experimental group

Description:

Patients with defective posterior maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and to be used for bone augmentation with sinus lift.

Treatment:

Other: autogenous bone

Mineralized Plasmatic Matrix (MPM)

Experimental group

Description:

Patients with defective posterior maxillary alveolar ridges requiring implant insertion will receive bone graft using Mineralized plasmatic matrix.

Treatment:

Other: Mineralized plasmatic matrix