Postoperative Analgesia After Elective Hip Surgery - Effect of Obturator Nerve Blockade

University of Aarhus

Status and phase: Completed; Phase 4

Conditions: Obturator Nerve Block; Total Hip Replacement

Treatments: Procedure: Obturator nerve block; Drug: Sodium Chloride 9mg/mL; Drug: Bupivacaine-epinephrine; Procedure: Sham block

Study type: Interventional

Funder types: Other

Identifiers

NCT03064165

HIP/FUSION#2

Details and patient eligibility

About

The study investigates the effect of an obturator nerve block on the postoperative pain and opioid consumption after total hip replacement.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients for primary hip replacement in spinal anesthesia
• Age >= 18 years
• American Society of Anesthesiologists physical status classification score I-III
• Informed consent

Exclusion criteria

• Lacking the ability to corporate
• Lacking the ability to speak danish
• Planned discharge on the same day of surgery
• Neuropathy of the lower extremities
• Contraindications for NonSteroidal Anti-Inflammatory Drugs (NSAID)
• Contraindications for dexamethasone
• Chronic opioid demanding pain
• Pregnancy
• Allergy towards one or both investigatory medicinal products
• Active treatment with amiodarone
• Active treatment with verapamil
• Active treatment with corticosteroids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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62 participants in 2 patient groups, including a placebo group

Obturator nerve block

Experimental group

Description:

Postoperative obturator nerve block with 15 mL bupivacain 5 mg/mL and epinephrine 5 µg/mL.

Treatment:

Procedure: Obturator nerve block

Drug: Bupivacaine-epinephrine

Sham block

Placebo Comparator group

Description:

Postoperative sham-block with normal saline.

Treatment:

Drug: Sodium Chloride 9mg/mL

Procedure: Sham block