Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy

University of Oslo (UIO)

Status and phase: Completed; Phase 4

Conditions: Living Donors

Treatments: Drug: Sugar pill; Drug: Pregabalin

Study type: Interventional

Funder types: Other

Identifiers

NCT01059331

2009/1286-1

Details and patient eligibility

About

The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of paracetamol, corticoids and ketobemidone.

In addition potential sideeffects as sedation and effect on cognitive function will be recorded.

Enrollment: 80 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18, < 75 years
• healthy patients accepted for laparoscopic living donor nephrectomy

Exclusion criteria

• not familiar to the Norwegian language (spoken and written)
• allergic to one or more of the medication given in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

Pregabalin

Experimental group

Treatment:

Drug: Pregabalin

Sugar pill

Placebo Comparator group

Treatment:

Drug: Sugar pill