Postoperative Analgesic Efficacy of Trans Abdominis Plane Block

Armed Forces Hospital, Pakistan

Status: Completed

Conditions: Cesarean Section Complications; Post Operative Pain

Treatments: Procedure: Trans abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT05831501

IERB/02/2023

Details and patient eligibility

About

Transverse abdominis plane (TAP) block is an effective method to manage postoperative pain in patients with midline abdominal wall incisions. It is used frequently in many lower abdominal surgeries however its use after caesarean section is still new, and fewer studies are available. We conducted this study to see the analgesic effect of TAP block after caesarean section.

Full description

The study is being conducted, at Combined Military Hospital Sargodha, Pakistan, to compare the analgesic efficacy of TAP block in providing post-caesarean analgesia with the control group, in terms of mean postoperative use of opioids after caesarean delivery. Sixty patients have been randomly selected using non-probability, consecutive sampling, and applying inclusion and exclusion criteria. The study design is a randomized controlled trial with thirty patients in each group undergoing elective caesareans. All patients will be given spinal anaesthesia with 1.5ml of 0.75% hyperbaric bupivacaine for a caesarean section. Patients in Group A will receive bilateral TAP block with 20ml of 0.25% bupivacaine while 20 ml of saline will be injected in patients of Group B on both sides of midline after caesarean section, in addition to intravenous ketorolac 8hrly. The intensity of pain, total opioid consumption, presence of vomiting, and sedation will be noted until 24 hours after the surgery.

Enrollment: 60 patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Elective Caesarean section
• ASA 1-3
• 20yrs to 45yrs

Exclusion criteria

• Emergency Surgery
• known allergy to local anaesthetic
• severe pre-eclampsia
• placenta accreta
• ASA 4
• Coagulopathy
• Hemodynamically unstable

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

TAP block group

Experimental group

Description:

At the end of the cesarean section, a TAP block will be given by Injecting of 20ml 0.25% Bupivacaine on both sides of the midline using ultrasound-guided subcostal approach

Treatment:

Procedure: Trans abdominis plane block

Placebo group

No Intervention group

Description:

At the end of the cesarean section, 20 ml of saline will be injected on both sides of the midline