ClinicalTrials.Veeva

Menu

Postoperative Atelectasis in Pediatric Patients With Prone Position

Seoul National University logo

Seoul National University

Status

Completed

Conditions

Pulmonary Atelectasis, Postoperative
Atelectasis, Compression

Treatments

Procedure: Repetitive recruitment with PEEP
Procedure: One recruitment with PEEP

Study type

Interventional

Funder types

Other

Identifiers

NCT03486847
H-1802-088-923

Details and patient eligibility

About

This study evaluates the incidence of postoperative atelectasis after general anesthesia with prone position using lung ultrasound in children age < 3 years.

Full description

Atelectasis is common in pediatric patients after general anesthesia. Particularly, infants are more likely to develop atelectasis or ventilation-perfusion imbalance after general anesthesia because of the immature ribs and respiratory muscles, the high compliance of the rib cage and a significant reduction in functional residual capacity (FRC) during general anesthesia. Previous studies have reported that alveolar recruitment and positive end-expiratory pressure (PEEP) can be used to reduce atelectasis in children. Also, previous studies have shown that the lung ultrasound can be used to evaluate the degree of atelectasis during general anesthesia in children.

However, none of the previous studies investigated the incidence of atelectasis, the effect of alveolar recruitment, and the PEEP in pediatric patients under general anesthesia with prone position. The purpose of this study was to evaluate previously described parameters using lung ultrasound.

Enrollment

74 patients

Sex

All

Ages

Under 3 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children undergoing general anesthesia with prone position
  • Endotracheal intubation and mechanical ventilation during general anesthesia
  • Operation time is more than 2 hours

Exclusion criteria

  • Previous lung surgery
  • Any abnormal findings such as atelectasis, pneumothorax, pleural effusion, or pneumonia on preoperative chest X-ray
  • Researchers judge (to be inappropriate)

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

74 participants in 2 patient groups

Repetitive recruitment with PEEP
Experimental group
Description:
One alveolar recruitment at before surgery and repetitive alveolar recruitment (once an hour) during surgery
Treatment:
Procedure: Repetitive recruitment with PEEP
One recruitment with PEEP
Active Comparator group
Description:
One alveolar recruitment at before surgery
Treatment:
Procedure: One recruitment with PEEP

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems