Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up

Lene Krenk

Status: Completed

Conditions: Postoperative Cognitive Dysfunction

Treatments: Other: no intervention, descriptive study

Study type: Observational

Funder types: Other

Identifiers

NCT01103752

H-3-2009-096

Details and patient eligibility

About

The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery. The hypothesis is that the fast-track methodology with a mean hospital stay less than 3 days will help to minimize this reduction in memory and concentration.

Enrollment: 225 patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 60 years of age or above
• ASA classification 1-4
• undergoing fast-track hip or knee replacement

Exclusion criteria

• anaesthesia within the past 90 days
• daily consumption of sleep or anxiety medication
• more than 35 units of alcohol per week
• lack of proper verbal and reading skills, Danish
• Serious hearing or visual impairment
• Mini mental status evaluation (MMSE) < 24
• Parkinsons Disease or other neurological disease causing functional impairment

Trial design

225 participants in 1 patient group

Surgery

Description:

This group (n=220) consist of patients undergoing hip or knee replacement in a fast-track setup and they are tested 3 times for postoperative cognitive dysfunction.

Treatment:

Other: no intervention, descriptive study