Postoperative Delirium in the ICU Setting of an Eastern European Centre

Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor

Status: Enrolling

Conditions: Cognitive Impairment; Postoperative Delirium

Treatments: Device: BIS monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT05474872

456/12.01.2022

Details and patient eligibility

About

The study targets postoperative delirium in patients undergoing major abdominal surgery, with the aim to evaluate the functional baseline and proteomics implicated in pathogenesis, prevention strategies (such as anesthesia depth monitoring) and incidence in certain population groups.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA risk I-III;
• patients undergoing complex digestive surgery, such as esophagectomy, total gastrectomy, hemicolectomy, cephalic duodenopancreatectomy, hepatic resection.

Exclusion criteria

• the impossibility of obtaining the patient's consent/his decisional incapacity;
• patients who underwent neurosurgery for cerebrospinal lesions / cardiac surgery under cardiopulmonary bypass;
• prediagnosed senile/vascular/mixed dementia.

Trial design

100 participants in 2 patient groups

BIS monitoring

Description:

Patients in this group will be subjected to Bispectral index-guided general anesthesia.

Treatment:

Device: BIS monitoring

PRST score monitoring

Description:

Patients in this group will be subjected PRST score-guided general anesthesia.