Postoperative Effects of TAP Block Versus QLB Type 2 Block

Bozyaka Training and Research Hospital

Status and phase: Completed; Phase 4

Conditions: Postoperative Pain; Inguinal Hernia

Treatments: Drug: Acetaminophen; Procedure: Inguinal Hernia Repair; Drug: Tramadol HCl; Drug: 0.25% Bupivacaine; Drug: 0.5% Bupivacaine+Glucose

Study type: Interventional

Funder types: Other

Identifiers

NCT03126084

ANES-QLB-0609

Details and patient eligibility

About

This study compares analgesic effectiveness of transversus abdominis plane block and quadratus lumborum block type 2 in open hernia repair surgery. All of the patients will receive routine intravenous analgesic regimen. In addition to that one-third of the patients will receive transversus abdominis plane block, one-third will receive quadratus lumborum block type 2. One-third of the patients will not receive any blocks and will constitute the control group

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who are over 18 years of age
• Patients who are scheduled for elective unilateral open hernia repair with tension free mesh techniques
• Patients who are in ASA's physical status score group 1 or 2

Exclusion criteria

• Patients who are younger than 18 years of age
• Patients who have severe stenotic heart diseases
• Patients who have bleeding diathesis
• Patients who have true allergies to local anesthetics
• Patients who have neurologic deficits corresponding to effect site of the anesthetic techniques

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 3 patient groups

TAP

Active Comparator group

Description:

Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose. Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia. Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.

Treatment:

Drug: 0.5% Bupivacaine+Glucose

Drug: 0.25% Bupivacaine

Drug: 0.25% Bupivacaine

Procedure: Inguinal Hernia Repair

Drug: Tramadol HCl

Drug: Acetaminophen

QLB2

Active Comparator group

Description:

Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose. Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia. Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.

Treatment:

Drug: 0.5% Bupivacaine+Glucose

Drug: 0.25% Bupivacaine

Drug: 0.25% Bupivacaine

Procedure: Inguinal Hernia Repair

Drug: Tramadol HCl

Drug: Acetaminophen

CONT

Active Comparator group

Description:

Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose. Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia. Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.

Treatment:

Drug: 0.5% Bupivacaine+Glucose

Procedure: Inguinal Hernia Repair

Drug: Tramadol HCl

Drug: Acetaminophen