Postoperative Hypofractionated Intensity-modulated Radiotherapy Endometrial Cancer

Samsung Medical Center

Status: Enrolling

Conditions: Endometrial Cancer

Treatments: Radiation: POHIM_EM

Study type: Interventional

Funder types: Other

Identifiers

NCT05876130

2022-09-123

Details and patient eligibility

About

To investigate the non-inferiority of disease-free survival in women who received hypofractionated intensity-modulated whole pelvic radiation therapy (2.5 Gy x 16 fractions) after curative surgery for stage III endometrial cancer.

Enrollment: 92 estimated patients

Sex: Female

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• histologically confirmed endometrioid type endometrial cancer
• completion of hysterectomy and surgical staging
• pathologically confirmed FIGO stage III
• ECOG performance status 0 or 1
• adjuvant chemotherapy was done or planned

Exclusion criteria

• presence of distant metastasis
• previous history of pelvic radiotherapy
• severe and unstable medical condition
• previous history of other carcinoma except for thyroid cancer, skin cancer, and endometrial cancer

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

92 participants in 1 patient group

POHIM_EM

Experimental group

Description:

adjuvant hypofractionated IMRT for endometrial cancer

Treatment:

Radiation: POHIM_EM